A pipeline of novel, disease-modifying drugs

Our RNA therapeutic drugs are splice-switching oligonucleotides (SSOs) that up-regulate a naturally occurring, anti-inflammatory spliceoform of RAGE ('esRAGE') in inflamed tissues.

          RBr042         RBr021         RBr07        RBr054

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Our peptide drugs block pro-inflammatory signalling from activated RAGE in inflamed tissue.

          RBp050